Human Embryonic and Induced Pluripotent Stem Cell Unit

The Human Embryonic and Induced Pluripotent Stem Cell Unit (HSCU) specializes in:

1. Human embryonic stem cell (ESC) culture, maintenance and differentiation
2. Generation of human induced pluripotent stem cells (iPSC) from somatic cells using cell reprogramming technologies
3. Directed differentiation of pluripotent stem cells (ESC, iPSC) for the development of 2D and 3D cellular systems for modeling brain development and pathology.

The HSCU, in the context of collaborative projects or service contracts, offers:
Preclinical drug evaluation in human iPSC-based models of neurodegenerative diseases

1. Generation of iPSC
2. Development of iPSC-derived cellular systems
3. Training in human stem cell culture principles, maintenance, and directed differentiation
4. Training in the analysis of iPSC-derived cellular systems of human neurodegenerative diseases
5. Consultancy for project development, protocol establishment, experimental design, troubleshooting